Midterm outcomes of transmyocardial laser revascularization with intramyocardial injection of adipose derived stromal cells for severe refractory angina

Transmyocardial Revascularization Transmyocardial Revascularization With CO2 Laser in Patients With Refractory Angina Pectoris Clinical Results from The Norwegian Randomized Trial

RESULTS Transmyocardial laser revascularization resulted in significant relief in angina symptoms after three and 12 months compared to baseline. Time to chest pain during exercise increased from baseline by 78 s after three months (p 5 NS) and 66 s (p , 0.01) after 12 months in the TMR group, whereas total exercise time and MVO2 were unchanged. No significant changes were observed in the MT gr...

Intermediate-term clinical outcome following transmyocardial laser revascularization in patients with refractory angina pectoris.

BACKGROUND This study was conducted to examine the intermediate-term clinical outcomes in patients with refractory angina pectoris treated with transmyocardial laser revascularization (TMR) at our institution. TMR is an alternative surgical technique for the treatment of myocardial ischemia and angina pectoris not amenable to conventional percutaneous or surgical revascularization. Limited data...

[Cell therapy plus transmyocardial laser revascularization: a proposed alternative procedure for refractory angina].

OBJECTIVE We tested the hypothesis that TMLR combined with intramyocardial injection of BMC is safe, and may help increase the functional capacity of patient with refractory angina. METHODS Nine patients (eight men), 65+/-5 years old, with refractory angina for multivessel disease and previous myocardial revascularization procedures (CABG/PCI), not candidates for another procedure due to the ...

The Heart Laser(TM): transmyocardial revascularization treatment of angina pectoris.

Transmyocardial laser revascularization.

Low-powered lasers were first used in the early 1980s to produce transventricular channels as an adjunct to coronary artery bypass graft surgery (CABG). Early results were encouraging, but because of the combined procedure, could not be attributed directly to use of the laser [1]. High-powered lasers were introduced into clinical practice in 1990 [2]. These lasers are powerful enough to create ...